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Creatine deficiency has been associated with severe neurodevelopmental delay, intellectual disability, behavioral abnormalities, poorly developed muscle mass and muscle weakness (Stockebrand etal, 2018

Its a good idea to give that change three months as well

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When you consume vitamin B12 as a supplement, your body may skip the first part of this process

This is the mechanistic basis for claims about mood and neurological effects, but the chain of inference from rodent dopamine modulation to human mood benefit is long and unvalidated

Aim for a modest caloric deficit of 300-500 calories below maintenance, with protein intake around 0.8-1 gram per pound of body weight