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By engaging this master switch, MOTS-c effectively mimics many of the cellular benefits of exercise and caloric restriction, positioning it as a powerful agent for improving systemic metabolic health

Br J Pharmacol 144:781790

Coleman JOD, Blake-Kalff MMA, Davies TGE (1997a) Detoxification of xenobiotics by plants: chemical modification and vacuolar compartmentation

So you can heat shock a worm or a fly, and they'd live 15% longer

It was very hard to identify a success story, Horton says

In therapeutic dosage, Drospirenone, a spironolactone analog, also possesses anti-androgenic and mild anti-mineralocorticoid properties