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Vitamin B12 plays a role in red blood cell production, DNA synthesis, and the proper functioning of the nervous system

In clinical trials, tirzepatide produced greater weight loss than semaglutide at comparable timepoints, suggesting more potent metabolic effects overall

This process acts as a sink for free cysteine and can lead to metabolic vulnerabilities and toxicity in NRF2-activated tumours

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Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells

Gaillard PJ, Appeldoorn CC, Dorland R, van Kregten J, Manca F, Vugts DJ, Windhorst B, van Dongen GA, de Vries HE, Maussang D, et al