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These findings highlight a bidirectional relationship: GLP-1 RAs can modulate the gut microbiota, while the pre-existing microbial configuration may influence therapeutic efficacy and reflect the degree of dysbiosis in T2D ( More recent real-world analyses on gut microbiome fecal samples of patients with T2D

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Searle T, Al-Niaimi F, Ali FR

These expanded uses position GLP-1s as multi-system therapies, not just treatments for diabetes or high obesity rates