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Assuming these are resolved in the coming years, there are still significant questions about how we can address the environmental sustainability challenges created by this new market and the vast patient population

doi: 10.1016/j.jnutbio.2020.108491, 220

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Warning signs include: Persistent right upper quadrant pain lasting more than 6 hours Fever (temperature above 100.4F or 38C) Severe nausea and vomiting Jaundice (yellowing of skin or eyes) Dark urine or pale stools Tenderness when pressing below the right rib cage Patients should also be aware that sudden severe epigastric pain radiating to the back, especially when accompanied by vomiting, may indicate pancreatitis, including gallstone-induced pancreatitis