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Metformin should be avoided if eGFR is below 30 mL/min/1.73m and used with caution between 30-45 mL/min/1.73m

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This is an important distinction that often causes confusion

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Estos resultados corresponden a la corrida analtica, no a las conclusiones de la literatura experimental

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The defect size is determined by comparing its diameter with the aortic annulus

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