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Dysregulation of this pathway can lead to impaired antioxidant defenses, contributing to neuronal damage and the progression of these disorders (Voma et al., 2014)

At pH 7.4, the net charge of p53 TAD PEP is -6.2

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Bukhari SS, Phillips BE, Wilkinson DJ, Limb MC, Rankin D, Mitchell WK, Kobayashi H, Greenhaff PL, Smith K, Atherton PJ

Thats published research going back to 1992