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Tendon fibroblast studies have additionally documented BPC-157 upregulation of growth hormone receptor (GHR) expression, a receptor that signals canonically through the JAK2-STAT pathway [2]

Subsequently, the samples were permeabilized with 0.3% Triton X-100 in PBS at room temperature for 10 min

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BPC-157 operates through multiple receptor systems

Monocarboxylate transporter 1 (MCT1) The bi-directional movement of monocarboxylic acids across the plasma membrane is catalyzed by a family of proton-linked monocarboxylate transporters (MCTs)

Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Set Variation Analysis (GSVA) analysis revealed significant activation of the glutathione metabolism pathway in drug-resistant breast cancer tissues compared to sensitive tissues after FEC (5-Fluorouracil, Epirubicin, and Cyclophosphamide) + docetaxel treatment (Fig