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Regarding the effects of metformin intervention, we focused on the treated MAFLD rats, where an evident increase in the expression of 1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide, DL-Norleucinamide, and Nudifloramide was observed, while expressions of D-Alloisoleucine, 3-[3-(Sulfooxy)phenyl] propanoic acid, 2-Methylbenzothiazole, 4-Heptenal diethyl acetal, 3alpha,7alpha,12alpha,25-Tetrahydroxy-5beta-cholestane-24-one, and Thioarginine decreased significantly
Q., Koehler, C
Ha JH, Kim JE, Kim YS
PMID 15459602
The neuroprotective effects are linked to the activation of the cAMP/PKA/pCREB pathway [45]
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