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3 Insulin resistance in type 1 diabetes Insulin resistance is associated with micro- and macrovascular complications in patients with T1D ( Supplementary Figure 1 )

Catrina AI, et al

As we age, our skin naturally becomes thinner, which contributes to a more aged appearance

This stiffening and structural distortion impair diastolic and eventually systolic function, making fibrosis a central determinant of adverse cardiovascular outcomes