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The long-acting strategies of GLP-1 drugs (amino acid substitutions, fatty acid side chain modifications, Fc fusion proteins, PEGylation) described in the article are only a small part of the current long-acting strategies, which have actually been applied to other protein-peptide drugs as early as
Sleep cycle regulation is vital for restorative sleep, which includes REM and non-REM stages
hFis1, a novel component of the mammalian mitochondrial fission machinery
A: Technically yes, but it is not recommended
In senescent cells, FOXO4 can help retain p53 in the nucleus, which supports a senescent survival state