252 For example, Zhan et al
Dosing Phases, Titration & Cycling The documented GLOW research schedule is a three-phase frequency taper rather than a dose-size titration
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It has been used for t2dm and obesity before also, starting from lira days
The FDAs stated rationale: Risk for immunogenicity, peptide-related impurities, and limited safety-related information. This represents precautionary regulationrestriction based on absence of proof rather than proof of harm