[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing
PMC 5282855
The Annals of Pharmacotherapy , 46 (2), 240247
Our Chairman , Martyn Hooper has also written books on it ( Amazon )
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