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Symptoms can include fatigue, weakness, memory loss, and neurological changes
It is possible that compensatory mechanisms could develop that reduce efficacy with prolonged use
In general cyanocobalamin isn't retained as long as hydroxocobalamin so maintenance dosing tends to be more frequent - think in the states they tend to do loading doses as daily for one or two weeks followed by weekly for a few months and then monthly
Mechanistic studies in preclinical models demonstrate that the presence of functional 3-adrenergic receptors is required for AOD 9604 activity
Cognitive function and mental clarity
Over time, eliminating in-office injections may also reduce costs
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