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Caution applies for individuals with cardiovascular conditions, though topical application minimizes systemic exposure
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We stimulated endothelial cells with nicotine while simultaneously introducing AAV-sh CXCL12 and control AAV (AAV-con), and the RT-qPCR analysis revealed that the expression of CXCL12 in endothelial cells was significantly downregulated after the addition of AAV-sh CXCL12 (Fig
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