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In the SURMOUNT-1 trial, side effects included: Nausea (31.0%) Diarrhoea (23.0%) Constipation (17.0%) Vomiting (12.0%) Despite higher weight loss than semaglutide in some studies, tolerability varies by individual

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For example, one case study reported worsened lactose intolerance and new gluten intolerance following semaglutide treatment for weight loss