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The Journal of Clinical Endocrinology & Metabolism, 110 (6), e2001e2007
It has been used for short-term weight management for over 60 years and typically produces results over 12 weeks
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In the semaglutide arm only, other non-prespecified baseline variables (age, ethnicity, diabetes status, sex, type of surgery, time since surgery (months), meal-stimulated change in GLP-1 at baseline, postoperative %WL (from DOS to randomization)) and maximum %WL achieved after surgery or MBS response (weight regain versus suboptimal post-surgery weight loss) were added to the primary outcome linear regression model for the semaglutide arm only (therefore omitting the treatment allocation covariate) to assess their relationship with %WL induced by semaglutide at 68 weeks
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