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Given that we previously demonstrated that b-AP15 inhibits NFB activity [16] and that NFB activity can prevent ROS induction [33, 34], we investigated if ROS are involved in b-AP15-mediated DR5 expression in HNSCC cells

The progression from single to dual to triple agonism has produced measurable advances in clinical research outcomes, and the category continues to evolve as additional compounds enter clinical development

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caution is required in patients with pancreatitis history, diabetic retinopathy, or during pregnancy