In an HG environment, 100 nM/500 nM 25-hydroxyvitamin D3 has been observed to exert a stimulatory effect on the proliferation of HRMECs, accompanied by an augmentation in GSH, SLC7A11, and GPX4
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Twice-weekly dosing may suit patients with rapid clearance but does not dramatically increase efficacy
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In fact, between 20-60% of obese people are metabolically healthy, while around 30% of normal-weight people are metabolically unhealthy