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In line with this, when the CV risk prediction model was applied to the semaglutide dataset it performed satisfactorily, both overall and when applied only to data from the glycemic efficacy trials, validating the utility of the LEADER model for this analysis
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doi: 10.1056/NEJMoa240334 Summary Keywords Prader-Willi syndrome, obesity, type 2 diabetes mellitus, GLP-1 RA, semaglutide, case report Citation Dinoi E, Daniele G, Michelucci A, Baldinotti F, Campi F, Marchetti P, Del Prato S and Dardano A (2025) Efficacy and safety of once-weekly semaglutide monotherapy in a young subject with Prader-Willi syndrome, obesity, and type 2 diabetes: a case report