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Front Clin Diab Health
10.1016/j.tibs.2016.05.008 215 PengM.YinN.LiM
GLP-1 drugs, or glucagon-like peptide-1 receptor agonists, are a class of medications used primarily to treat type 2 diabetes and obesity
Its sequence AcNlecyclo[AspHisDPheArgTrpLys]NH incorporates a norleucine substitution, a Dphenylalanine substitution, and a lactam bridge that cyclises the molecule, conferring markedly greater stability and resistance to enzymatic degradation than the native linear hormone
Anderson, M
Sin embargo, las formas compuestas carecen de las caractersticas de seguridad de los productos originales, como las cpsulas dosificadoras precargadas
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