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This translocation activates toll-like receptors (TLRs), including TLR4, in microglial cells within the brain, triggering neuroinflammatory responses

Non-enzymatic Binding and Intracellular Transport In addition to their catalytic function, GSTs also serve as non-enzymatic carrier proteins or ligandins (Habig et al., 1974

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10.5534/wjmh.230232 51 GuoX.ChiS.CongX.LiH.JiangZ.CaoR.et al (2015)

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While the study focused on enhancing antioxidant capacity, these improvements in redox balance are strongly linked to better insulin sensitivity and glucose regulation