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Presented for research literature review only Ahmadpour S et al

Disease activity was assessed utilizing the DAS28-CRP, a composite score that incorporates the count of tender and swollen joints, the patient's overall evaluation of disease activity, and the level of CRP

Eventually, nine RCTs conducted in Iran, Italy, China, and Japan involving a total of 508 participants were included in the meta-analysis

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For skin : Direct subcutaneous injection into areas of concern (face, neck, dcolletage) or systemic administration with localized topical application for synergistic effect

10.1534/genetics.119.302939 27 IzadiA.EbrahimiS.ShiraziS.TaghizadehS.ParizadM.FarzadiL.et al (2019)