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Monotherapy protocols are commonly initiated at 0.6 mg per week and escalated to a maximum studied dose of 4.5 mg as tolerated

Once released, GH travels to the liver where it stimulates production of insulin-like growth factor 1

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This short, synchronized half-life profile is why this version is preferred for pulsatile GH research, in contrast to CJC-1295 with DAC which has a ~8-day half-life and produces continuous receptor activation