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doi: 10.1111/j.1399-302X.2004.00155.x 6 BautersT
ROS damages the genetic code of the enzymes involved in transmethylation and transsulfuration and increases the degradation of GSH and the free radical hydrogen sulfide (H2S) produced
Billington, C
Immortalized cell lines are popular tools to study drug hepatotoxicity because they are cost effective, readily available as cryopreserved cells, can be of human origin and generally show robust proliferation
Arachidonate 12-lipoxygenase (ALOX12) inactivation diminishes p53-mediated ferroptosis induced by ROS stress (Chu et al., 2019)
doi:10.1101/cshperspect.a025395 31
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