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Animal models show anti-anxiety-like and pain-reducing effects, probably running through GHK-Cus broad gene modulation and inflammation pathways rather than any direct hit on neuroreceptors

Chronic treatment should be done with an oral preparation in patients with normal intestinal absorption

However, humans have far fewer GLP-1 receptors in thyroid C-cells than rodents

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The evolution from daily injections to weekly injections to oral tablets to patches reflects a clear industry trajectory toward making these therapies as frictionless as possible