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Potential therapeutic targets are low-grade systemic inflammation, oxidative stress, NO signaling, RAAS signaling, ECM remodeling, calcification, VSMCs, and cellular senescence
It was originally derived from a protective gastric peptide sequence, and much of the research has focused on mucosal protection, ulcer healing, intestinal inflammation, and gut barrier support
Accessed March 22, 2018
For approved indications, they can only be dispensed by licensed pharmacies and prescribed by certified medical professionals
(The Cochrane Collaboration) (July 21, 2003)
High retinol intake during pregnancy poses teratogenic risks to the developing foetus
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