For patients on established B12 injection therapy, monitoring is based primarily on clinical response and haematological parameters rather than routine serum B12 measurements, which may remain very high without indicating harm or overtreatment
NNMT is over-expressed in fat and liver tissue in obese, diabetic animals, and genetic knockdown of NNMT protects mice against diet-induced obesity by increasing energy expenditure
What is 5-Amino-1MQ Peptide Therapy
The standard schedule keeps each injection at 2.8 mg: daily in weeks 14, 5x per week in weeks 58, and 2-3x per week in weeks 912
Scientific References Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial
Pregnant or breastfeeding women who suspect B12 deficiency should have their levels tested by their prenatal care provider, who can recommend the appropriate supplementation route and dosage