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The modulatory role of GLP-1 on reward responses across different populations GLP-1 in obesity and T2D Obesity is mechanistically linked with T2D since individuals with a diagnosis of T2D are often obese and it is the main risk factor for developing T2D (Leitner et al., 2017)

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Obesity rates among adults have more than doubled since 1990, from 7% to 16% in 2022, according to the World Health Organization (WHO)

4.3 Activated open conducting state Recent studies have provided a significant breakthrough in understanding the activation gating mechanism in KARs