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Their analysis found no statistically significant increase in thyroid cancer risk in patients treated with semaglutide compared to those receiving placebo or other anti-diabetes medications

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This central effect is a key reason why GLP-1 agonists are so effective for weight loss

The copper side of the molecule matters too

In addition, these hormones are rapidly (within minutes) broken down by the enzyme dipeptidyl peptidase-4 (DPP-4), which poses an obvious problem for their potential therapeutic use