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It results from damage to the nerves of the hands and feet, causing pain and loss of function

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In the multiple ascending dose cohorts, weight loss was maintained for up to 150 days after the last dose

doi: 10.1186/s12986-017-0202-6 139 PuriPMirshahiFCheungONatarajanRMaherJWKellumJMet al

With a shorter half life and daily administration, liraglutide can have a moderate impact on caloric intake that is thought to help patients maintain their love of nutritious food