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doi: 10.3389/fphys.2020.00694 256 SharmaA.TiwariS.DebM

The result is a system where several tricks stack: a protease- and DPP-4-resistant peptide, a localized permeation enhancer, and strict administration rules (empty stomach, minimal water, a post-dose fasting window) that minimize the variability described earlier

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If the bioavailability is low, those milligrams won't reach your cells

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