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Following the compete transection of the quadriceps muscle in rats, a traumatic definitive defect under normal healing conditions would not be compensated (Staresinic et al

Risks of Improper Handling Loss of activity Aggregation and insolubility Bacterial contamination Chemical degradation Inconsistent results Pre-Reconstitution Preparation Sterility: Always work in a clean environment

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But complementary mechanisms on paper do not guarantee additive benefits or safety in a living patient combination effects have not been rigorously tested in humans, and stacking multiplies the unknowns rather than dividing the risk

2004 Mar;89(3):1217-21