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Current Status for Compounders Consistent with FDAs February 11, 2025 update, which remains in effect given the Courts denial of the PI and stay, FDAs approach to compounders is as follows: For a state-licensed pharmacy or physician compounding under section 503A of the FDCA, the period of enforcement discretion described below has ended

The COA documents HPLC purity, mass spectrometry identity confirmation, batch number, production date, and storage recommendations

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Abdominal pain: Mild stomach discomfort or bloating may appear early in treatment

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The following CVOTs, relative to DPP-4i and GLP-1RAs, have been identified and included in this review: EXAMINE, SAVOR-TIMI53, TECOS, CARMELINA, CAROLINA, ELIXA, SUSTAIN 6, EXSCEL, HARMONY, LEADER, PIONEER 6, REWIND, and AMPLITUDE-O [47,48,49, 53, 54, 56,57,58,59,60,61,62,63]