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Improved tolerability for sensitive individuals
PMID: 24788549, DOI: 10.1001/jama.2014.3695
Lifestyle and dietary guidance SemaPen emphasises genuine lifestyle change
And it disrupts sleep architecture, even when it seems to help you fall asleep faster
Across 13 trials that measured pain intensity, tramadol produced a mean reduction of 0.93 points on a standard zero-to-10 numerical rating scale compared to placebo
10.1007/s12031-018-1155-6 J
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