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No , B12 usually has the opposite effect

NAD+ therapy aids mitochondrial health, energy, cognition, and inflammation.[20][33][39] IV forms provide rapid boosts, with studies showing safety and efficacy in fatigue reduction

Deficiencies in vitamin B12 can significantly affect energy levels since it is responsible for red blood cell production and oxygen transport

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Lee KY, Russell SJ, Ussar S, Boucher J, Vernochet C, Mori MA, et al

She specializes in all things health and wellness, particularly dietary supplements and nutrition