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A patient needs to be relatively free of symptoms ( and this can take more than two years) in order to quietly start phasing out treatment
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LDH liquiform Kit Insert
Boxplot of HK3 phosphorylation at S191 and S67 sites across AML phenotypes (n = 162 patients)
We estimated that with this sample size, the study would have 80% power to detect an absolute difference in the rate of improvement in ALT of 30 percentage points, with a two-sided type 1 error of 0.05
Schnzer W, Thevis M
