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However, given the similar clinical efficacy and safety profiles amongst the available agents within the DPP-4 class of medications, the published head-to-head trials reviewed in this manuscript represent a good comparison of the two classes of medications (26, 35)

One instance where people should not take Semaglutide GLP-1 is if they are experiencing or have a history of pancreatitis

Herman, G

Biased agonism: one receptor, different signals Where is the GLP-1 receptor actually found