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[1] [2] As of 2024, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and it remains unavailable as a licensed medicine in the UK
As exclusivity ends, generic and biosimilar competition is expected to intensify, potentially reducing market share and pricing flexibility for current manufacturers
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In a preclinical study, sc semaglutide reduced hepatic TAGs and decreased the expression of 3 of 5 collagen genes and other inflammatory markers responsible for the development of liver fibrosis [50]
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