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In published in-vitro and animal research, GHRH analogs such as tesamorelin and Modified GRF (1-29) have been investigated for their ability to stimulate pituitary somatotrophs, while ipamorelin has been studied as a selective GH secretagogue reported to have minimal effect on cortisol or prolactin in animal models
Tesamorelin a GHRH analogue raising endogenous growth hormone, the whole-hormone comparator
Both flagged some examples as posing potential legal risks, under statutes that limit the claims health care providers can make about drugs that are not FDA-approved
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