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The type of niacinamide used in skincare is synthetically created
They accomplish this by binding to specific receptors on cell surfaces and activating biological pathways that stimulate tissue repair, reduce inflammation, and improve circulation to injured areas
It also includes glycosaminoglycans (GAGs), proteoglycans, fibronectin, and various growth factors that maintain tissue hydration, resilience, and repair capacity
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Direct head-to-head data against tirzepatide showed CagriSema underperforming the highest tirzepatide dose at 84 weeks meaning monotherapy claims of comparable efficacy are not supported by current Phase 3 evidence