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"Hepatocytes: A key role in liver inflammation." Front Immunol
[2] [3] Additionally, because the compound promotes blood vessel formation (angiogenesis), there are theoretical concerns about potential cancer promotion that require further investigation
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Of note, the dNK-like cell production of angiogenin and VEGF was dependent on STAT-3 and STAT-5 activation, whereas the production of MMP-9, TIMP-1, and TIMP-2 was STAT-3/5-independent (109)
AXL/MERTK inhibitor ONO-7475 potently synergizes with BCL2 inhibitor ABT-199, overcomes ABT-199 resistance mechanisms, and kills FLT3 ITD AML cells
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