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362 Uric acid-lowering drugs can be broadly classified into three major groups: drugs that reduce uric acid synthesis (xanthine oxidase inhibitors), drugs that promote uric acid excretion (reabsorption inhibitors), and drugs that regulate uric acid metabolic hydrolysis (uricase inhibitors)
Functional and phenotypic analyses confirm the induction of a pancreatic endocrine fate, including positive dithizone (DTZ) staining indicative of insulin production, as well as the upregulation of key pancreatic markers such as Nestin , PDX-1 , paired box gene 4 ( PAX4 ), neurogenin 3 ( NGN3 ), Isl-1, MAFA, insulin, and glucose transporter 2 ( GLUT2 )
1 Approved under the brand name Zepbound in the U.S
Application: Laboratory & in-vitro research only
Tyler Brooks said the program's ongoing support helped keep him motivated