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Neuropsychiatric symptoms such as depression, irritability, and personality changes may also occur

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The SURPASS trials demonstrated stable or improved kidney function in the tirzepatide groups compared to placebo, suggesting long-term kidney benefits that outweigh the short-term risks from GI-related dehydration

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Preliminary studies suggest that Semaglutide and other GLP-1 medications may reduce alcohol cravings: Animal Studies: Research on rats showed reduced alcohol intake and avoidance of relapse when treated with Semaglutide

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