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Some individuals maintain weight loss long-term, especially when consistent routines are in place
Weight regain after discontinuation of GLP-1-class agents is nearly universal, making retatrutide a long-term management commitment, not a finite treatment course
The landmark STEP 1 trial demonstrated mean reductions of 14.9% over 68 weeks, making it one of today's most effective pharmaceutical interventions
Tapering Requirements When taking prednisone for more than a few weeks, gradual dose reduction (tapering) becomes essential
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