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Any prescription of a drug for an off-label use must be made at the sole discretion and professional medical judgment of the prescribing physician

[6] In 2023, it was the 63rd most commonly prescribed medication in the United States, with more than 10 million prescriptions

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Type 2 diabetes models: Because the peptide affects blood-sugar signaling, researchers also look at it in metabolic and diabetes-related research

Unlike pure GLP-1 agonists, glucagon receptor activation can increase hepatic glucose output and may require careful monitoring in patients with diabetes