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This can therefore impact fertility in those with issues relating to obesity or hormonal imbalances

These effects are linked to its ability to normalize nitric oxide production, regulate oxidative balance, and maintain microvascular integrity across multiple tissues

Key priorities include: (i) reproductive-oriented RCTs with live birth or cumulative live birth as primary endpoints and standardized washout templates

As a result, contemporary guidelines recommend aspirin only for carefully selected populations, such as individuals with elevated cardiovascular risk or hereditary colorectal cancer syndromes