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In recent years, the functionality and complexity of in vitro BBB models have increased
GPanisello-RosellA.Sanchez-NunoS.AlvaN.Rosell-CatafauJ.CarbonellT
Do not exceed the suggested use
In addition, intranasal administration offers the potential advantages of a more rapid onset of action and avoidance of first-pass metabolism [28]
doi:10.1016/j.arcmed.2014.03.006 77
This mismatch is especially consequential given that Hispanic or Latino individuals are 17% more likely, and non-Hispanic Black individuals 60% more likely, to have type 2 diabetes than non-Hispanic White individuals ( [82] )
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