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These options are still under investigation and are not yet part of routine clinical care
Dual GLP-1/GIP agonists, such as tirzepatide, primarily enhance glycemic control and insulin sensitivity through synergistic incretin and -cell effects, producing the most pronounced HbA1c reductions among all classes
It is FDA-approved for Type 2 diabetes, cardiovascular risk reduction, and kidney disease
However, side effects cannot be hidden forever
and T.Y
Highlights of Prescribing Information - MOUNJARO Highlights of Prescribing Information - OZEMPIC Highlights of Prescribing Information - WEGOVY Highlights of Prescribing Information - ZEPBOUND Once-Weekly Semaglutide in Adults with Overweight or Obesity - The New England Journal of Medicine The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials - Diabetes Therapy Tirzepatide as Compared with Semaglutide for the Treatment of Obesity - The New England Journal of Medicine Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes - The New England Journal of Medicine Tirzepatide Versus Semaglutide on Weight Loss in Type 2 Diabetes Patients: A Systematic Review and MetaAnalysis of Direct Comparative Studies - Endocrinology, Diabetes & Metabolism
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