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If tirzepatide improves intestinal barrier function while reducing systemic inflammation through weight loss and metabolic improvement, it could theoretically address one of the upstream drivers of autoimmune disease activity

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The NHS is already tackling obesity in innovative ways, including through community care models and digital technologies, to help deliver these drugs as part of a rounded package of care.

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Olanow CW, Brundin P (2013) Parkinsons disease and alpha synuclein: is Parkinsons disease a prion-like disorder